[HTML][HTML] Stems cells and the pathways to aging and cancer
DJ Rossi, CHM Jamieson, IL Weissman - Cell, 2008 - cell.com
DJ Rossi, CHM Jamieson, IL Weissman
Cell, 2008•cell.comThe aging of tissue-specific stem cell and progenitor cell compartments is believed to be
central to the decline of tissue and organ integrity and function in the elderly. Here, we
examine evidence linking stem cell dysfunction to the pathophysiological conditions
accompanying aging, focusing on the mechanisms underlying stem cell decline and their
contribution to disease pathogenesis.
central to the decline of tissue and organ integrity and function in the elderly. Here, we
examine evidence linking stem cell dysfunction to the pathophysiological conditions
accompanying aging, focusing on the mechanisms underlying stem cell decline and their
contribution to disease pathogenesis.
The aging of tissue-specific stem cell and progenitor cell compartments is believed to be central to the decline of tissue and organ integrity and function in the elderly. Here, we examine evidence linking stem cell dysfunction to the pathophysiological conditions accompanying aging, focusing on the mechanisms underlying stem cell decline and their contribution to disease pathogenesis.
cell.com