Molecular basis of giant cells in tuberous sclerosis complex
DJ Kwiatkowski, BD Manning - New England Journal of Medicine, 2014 - Mass Medical Soc
New England Journal of Medicine, 2014•Mass Medical Soc
Molecular Basis of Giant Cells in Tuberous Sclerosis Complex | NEJM Skip to main content
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The clinical observation of giant-cell brain tumors in a 15-year-old girl with epilepsy (the first patient noted to have tuberous sclerosis) has led to elucidation of the mTOR pathway, a critical regulator of cell size and growth.
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