Cholesterol and sphingolipids as lipid organizers of the immune cells' plasma membrane: their impact on the functions of MHC molecules, effector T-lymphocytes and …
The possible regulatory mechanisms by which glycosphingolipid-and cholesterol-rich
membrane microdomains, caveolar and non-caveolar lipid rafts, control the immune
response are continuosly expanding. In the present overview we will focus on how these
membrane-organizing lipids are involved, in collaboration with tetraspanin proteins, in the
formation of distinct MHC-I and MHC-II microdomains at the cell surface and will analyze the
possible roles of MHC compartmentation in the processes of antigen presentation and …
membrane microdomains, caveolar and non-caveolar lipid rafts, control the immune
response are continuosly expanding. In the present overview we will focus on how these
membrane-organizing lipids are involved, in collaboration with tetraspanin proteins, in the
formation of distinct MHC-I and MHC-II microdomains at the cell surface and will analyze the
possible roles of MHC compartmentation in the processes of antigen presentation and …