Maternal complications and perinatal mortality: findings of the World Health Organization Multicountry Survey on Maternal and Newborn Health

JP Vogel, JP Souza, R Mori, N Morisaki… - … Journal of Obstetrics …, 2014 - Wiley Online Library
JP Vogel, JP Souza, R Mori, N Morisaki, P Lumbiganon, M Laopaiboon, E Ortiz‐Panozo
BJOG: An International Journal of Obstetrics & Gynaecology, 2014Wiley Online Library
Objective We aimed to determine the prevalence and risks of late fetal deaths (LFD s) and
early neonatal deaths (END s) in women with medical and obstetric complications. Design
Secondary analysis of the WHO Multicountry Survey on Maternal and Newborn Health
(WHOMCS). Setting A total of 359 participating facilities in 29 countries. Population A total of
308 392 singleton deliveries. Methods We reported on perinatal indicators and determined
risks of perinatal death in the presence of severe maternal complications (haemorrhagic …
Objective
We aimed to determine the prevalence and risks of late fetal deaths (LFDs) and early neonatal deaths (ENDs) in women with medical and obstetric complications.
Design
Secondary analysis of the WHO Multicountry Survey on Maternal and Newborn Health (WHOMCS).
Setting
A total of 359 participating facilities in 29 countries.
Population
A total of 308 392 singleton deliveries.
Methods
We reported on perinatal indicators and determined risks of perinatal death in the presence of severe maternal complications (haemorrhagic, infectious, and hypertensive disorders, and other medical conditions).
Main outcome measures
Fresh and macerated LFDs (defined as stillbirths ≥ 1000 g and/or ≥28 weeks of gestation) and ENDs.
Results
The LFD rate was 17.7 per 1000 births; 64.8% were fresh stillbirths. The END rate was 8.4 per 1000 liveborns; 67.1% occurred by day 3 of life. Maternal complications were present in 85.6, 86.5, and 88.6% of macerated LFDs, fresh LFDs, and ENDs, respectively. The risks of all three perinatal mortality outcomes were significantly increased with placental abruption, ruptured uterus, systemic infections/sepsis, pre‐eclampsia, eclampsia, and severe anaemia.
Conclusions
Preventing intrapartum‐related perinatal deaths requires a comprehensive approach to quality intrapartum care, beyond the provision of caesarean section. Early identification and management of women with complications could improve maternal and perinatal outcomes.
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