[HTML][HTML] Elements of neural adhesion molecules and a yeast vacuolar protein sorting receptor are present in a novel mammalian low density lipoprotein receptor …
H Yamazaki, H Bujo, J Kusunoki, K Seimiya… - Journal of Biological …, 1996 - ASBMB
Normal cell development depends to a large part on multifunctional proteins that have
evolved by recombination of proven modular elements. We now have discovered and
characterized in rabbit such a multi-domain protein, and classify it as novel member of the
low density lipoprotein (LDL) receptor gene family. The extracellular portion of the~ 250-kDa
membrane protein, termed LR11, contains a cluster of 11 LDL receptor ligand binding
repeats, a group of 5 LDL receptor" YWTD" repeats, a large hexarepeat domain of structural …
evolved by recombination of proven modular elements. We now have discovered and
characterized in rabbit such a multi-domain protein, and classify it as novel member of the
low density lipoprotein (LDL) receptor gene family. The extracellular portion of the~ 250-kDa
membrane protein, termed LR11, contains a cluster of 11 LDL receptor ligand binding
repeats, a group of 5 LDL receptor" YWTD" repeats, a large hexarepeat domain of structural …