[HTML][HTML] Upregulation of capsule enables Streptococcus pyogenes to evade immune recognition by antigen-specific antibodies directed to the G-related α2 …
K Dinkla, I Sastalla, AW Godehardt, N Janze… - Microbes and …, 2007 - Elsevier
One of the major problems associated with the development of a vaccine against
Streptococcus pyogenes is the ability of this pathogen to escape recognition by antibodies
directed against conserved surface-associated determinants and to establish infection in the
setting of an acquired immune response. Identification of the mechanism (s) used by S.
pyogenes to avoid recognition by antigen-specific antibodies and escape killing in blood
was the focus of this study. We showed here that S. pyogenes was capable of surviving in …
Streptococcus pyogenes is the ability of this pathogen to escape recognition by antibodies
directed against conserved surface-associated determinants and to establish infection in the
setting of an acquired immune response. Identification of the mechanism (s) used by S.
pyogenes to avoid recognition by antigen-specific antibodies and escape killing in blood
was the focus of this study. We showed here that S. pyogenes was capable of surviving in …