In recent years, our knowledge of the immunopathogenesis of chronic inflammatory skin
diseases has increased significantly. Accumulating evidence indicates that the complex
interaction of structural cells, in particular keratinocytes and endothelial cells, with skin-
infiltrating leukocytes is key to our understanding of psoriasis. The recruitment of pathogenic
leukocyte subsets into the skin represents a prerequisite for the initiation and maintenance
of psoriasis vulgaris and is mediated by a complex chemokine and cytokine network …