[HTML][HTML] Discordant regulation of microRNA between multiple experimental models and human pulmonary hypertension
K Schlosser, M Taha, Y Deng, B Jiang, DJ Stewart - Chest, 2015 - Elsevier
BACKGROUND The dysregulation of microRNA (miRNA) is known to contribute to the
pathobiology of pulmonary arterial hypertension (PAH). However, the relationships between
changes in tissue and circulating miRNA levels associated with different animal models and
human pulmonary hypertension (PH) have not been defined. METHODS A set of miRNAs
that have been causally implicated in PH, including miR-17,− 21,− 130b,− 145,− 204,− 424,
and− 503, were measured by reverse transcription-quantitative polymerase chain reaction in …
pathobiology of pulmonary arterial hypertension (PAH). However, the relationships between
changes in tissue and circulating miRNA levels associated with different animal models and
human pulmonary hypertension (PH) have not been defined. METHODS A set of miRNAs
that have been causally implicated in PH, including miR-17,− 21,− 130b,− 145,− 204,− 424,
and− 503, were measured by reverse transcription-quantitative polymerase chain reaction in …