Total and specific IgE in nasal polyps is related to local eosinophilic inflammation
C Bachert, P Gevaert, G Holtappels… - Journal of allergy and …, 2001 - Elsevier
Background: Nasal polyps (NPs) are characterized by eosinophilic inflammation and often
coexist with asthma. However, the role of atopy and IgE in NP pathogenesis is unclear.
Objective: We sought to determine whether there is an association between total and
specific IgE to a variety of allergens in polyp and nonpolyp tissue and markers of
eosinophilic inflammation or skin test results. Methods: Homogenates were prepared from
nasal tissue of 20 patients with NPs and 20 patients without NPs and analyzed for …
coexist with asthma. However, the role of atopy and IgE in NP pathogenesis is unclear.
Objective: We sought to determine whether there is an association between total and
specific IgE to a variety of allergens in polyp and nonpolyp tissue and markers of
eosinophilic inflammation or skin test results. Methods: Homogenates were prepared from
nasal tissue of 20 patients with NPs and 20 patients without NPs and analyzed for …