The c-erb-A gene encodes a thyroid hormone receptor

C Weinberger, CC Thompson, ES Ong, R Lebo… - Nature, 1986 - nature.com
C Weinberger, CC Thompson, ES Ong, R Lebo, DJ Gruol, RM Evans
Nature, 1986nature.com
The c-erb-A gene encodes a thyroid hormone receptor Page 1 NATURE VOL. 324 18/25
DECEMBER 1986 ARTICLES– ––- - - -- ––-– “* The c-erb-A gene encodes a thyroid hormone
receptor Cary Weinberger", Catherine C. Thompson", Estelita S. Ong", Roger Lebo", Donald J.
Gruolº & Ronald M. Evans' * Howard Hughes Medical Institute, Gene Expression Laboratory,
and § Regulatory Biology Laboratory, The Salk Institute for Biological Studies, PO Box 85800,
San Diego, California 92138, USA † Department of Biology, University of California, San Diego …
Abstract
The cDNA sequence of human c-erb-A, the cellular counterpart of the viral oncogene v-erb-A, indicates that the protein encoded by the gene is related to the steroid hormone receptors. Binding studies with the protein show it to be a receptor for thyroid hormones.
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