Suppression of plasma hepcidin by venesection during steady-state hypoxia
NP Talbot, TG Smith, S Lakhal-Littleton… - Blood, The Journal …, 2016 - ashpublications.org
Blood, The Journal of the American Society of Hematology, 2016•ashpublications.org
Hepcidin inhibits iron uptake from the gut and release of iron from macrophages in the
reticuloendothelial system. Suppression of plasma hepcidin occurs in lowlanders after
ascent to high altitude, 1, 2 reflecting the increased iron demand for erythropoiesis, but the
mechanism and primary stimulus for hepcidin suppression in this setting remains unclear.
reticuloendothelial system. Suppression of plasma hepcidin occurs in lowlanders after
ascent to high altitude, 1, 2 reflecting the increased iron demand for erythropoiesis, but the
mechanism and primary stimulus for hepcidin suppression in this setting remains unclear.
Hepcidin inhibits iron uptake from the gut and release of iron from macrophages in the reticuloendothelial system. Suppression of plasma hepcidin occurs in lowlanders after ascent to high altitude, 1, 2 reflecting the increased iron demand for erythropoiesis, but the mechanism and primary stimulus for hepcidin suppression in this setting remains unclear.
ashpublications.org