In vitro cultivation of the exoerythrocytic stage of Plasmodium berghei in a hepatoma cell line.
MR Hollingdale, P Leland… - The American journal of …, 1983 - europepmc.org
MR Hollingdale, P Leland, AL Schwartz
The American journal of tropical medicine and hygiene, 1983•europepmc.orgWhen inoculated with sporozoites of Plasmodium berghei, a line of hepatoma cells (HepG2-
A16) derived from human liver supports the complete asexual developmental cycle of the
exoerythrocytic stage. Parasites were shown to resemble parasites in vivo in hepatocytes.
Subinoculation of merozoites into mice induced a red blood cell infection.
A16) derived from human liver supports the complete asexual developmental cycle of the
exoerythrocytic stage. Parasites were shown to resemble parasites in vivo in hepatocytes.
Subinoculation of merozoites into mice induced a red blood cell infection.
When inoculated with sporozoites of Plasmodium berghei, a line of hepatoma cells (HepG2-A16) derived from human liver supports the complete asexual developmental cycle of the exoerythrocytic stage. Parasites were shown to resemble parasites in vivo in hepatocytes. Subinoculation of merozoites into mice induced a red blood cell infection.
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