Influence of cold ischemia time in combination with donor acute kidney injury on kidney transplantation outcomes
Y Xia, P Friedmann, CM Cortes, ML Lubetzky… - Journal of the American …, 2015 - Elsevier
Background Deceased-donor kidneys are often exposed to ischemic events from donor
instability, as evidenced by acute kidney injury (AKI). Clinicians may be reluctant to
transplant kidneys with AKI that also have prolonged cold ischemia time (CIT) for fear of an
additional deleterious effect. Study Design We evaluated national data between 1998 and
2013 of adult first-time kidney-only recipients of paired kidneys from donors with AKI
(terminal serum creatinine≥ 2 mg/dL), in which the CIT difference between recipients was≥ …
instability, as evidenced by acute kidney injury (AKI). Clinicians may be reluctant to
transplant kidneys with AKI that also have prolonged cold ischemia time (CIT) for fear of an
additional deleterious effect. Study Design We evaluated national data between 1998 and
2013 of adult first-time kidney-only recipients of paired kidneys from donors with AKI
(terminal serum creatinine≥ 2 mg/dL), in which the CIT difference between recipients was≥ …