Interleukin-6 as a first-rated serum inflammatory marker to predict mortality and hospitalization in the oldest old: A regression and CART approach in the BELFRAIL …

W Adriaensen, C Matheď, B Vaes… - Experimental …, 2015 - Elsevier
Background Certain inflammatory biomarkers increase with age, provide information about
general burden of illness and could cause or reflect any collateral damage to healthy cells
and organs. However, comparative studies to predict adverse outcomes are missing.
Therefore, our study validated and identified the principal prognostic marker to predict
important adverse outcomes in the oldest old from an extensive battery of serum
inflammatory markers. Methods A large battery of potential 'inflammaging'markers (IL-1α, IL1 …