Abdominal aortic aneurysm (AAA) is a common disease associated with significant
cardiovascular morbidity and mortality. The pathogenesis of AAA is poorly defined, making
targeting of new therapies problematic. Current evidence favours an interaction of multiple
environmental and genetic factors in the initiation and progression of AAA. Epigenetics is the
term used to define the properties of the genome that are not explained by the primary
sequence, but are due to the modifications of DNA and/or associated proteins. Previous …