Cancer biomarkers are invaluable tools for cancer detection, prognosis, and treatment.
Recently, microvesicles have appeared as a novel source for cancer biomarkers. We
present here the results from a proteomic analysis of microvesicles released to the
extracellular environment by the metastatic prostate cancer cell line PC-3. Using
nanocapillary liquid chromatography-tandem mass spectrometry 266 proteins were
identified with two or more peptide sequences. Further analysis showed that 16% of the …