Mathematical formulae for the prediction of the residual beta cell function during the first two years of disease in children and adolescents with insulin-dependent …

Y Klipper-Aurbach, M Wasserman… - Medical hypotheses, 1995 - Elsevier
On the basis of a retrospective study of 71 children followed for 24 months after diagnosis of
type I insulin dependent diabetes a fitted mathematical model was constructed for the
prediction of the course of beta cell function from the time of diagnosis. Two equations were
derived, one for the maximal basal (B-max) and the other for the maximal iv glucagon
stimulated peak C-peptide (P-max) levels reached during the remission period. The
prognostic variables selected for analysis were: peak C-peptide levels at diagnosis (Po) …