Genetic analysis of novel avian A (H7N9) influenza viruses isolated from patients in China, February to April 2013
T Kageyama, S Fujisaki, E Takashita, H Xu… - …, 2013 - eurosurveillance.org
T Kageyama, S Fujisaki, E Takashita, H Xu, S Yamada, Y Uchida, G Neumann, T Saito…
Eurosurveillance, 2013•eurosurveillance.orgNovel influenza viruses of the H7N9 subtype have infected 33 and killed nine people in
China as of 10 April 2013. Their haemagglutinin (HA) and neuraminidase genes probably
originated from Eurasian avian influenza viruses; the remaining genes are closely related to
avian H9N2 influenza viruses. Several characteristic amino acid changes in HA and the PB2
RNA polymerase subunit probably facilitate binding to human-type receptors and efficient
replication in mammals, respectively, highlighting the pandemic potential of the novel …
China as of 10 April 2013. Their haemagglutinin (HA) and neuraminidase genes probably
originated from Eurasian avian influenza viruses; the remaining genes are closely related to
avian H9N2 influenza viruses. Several characteristic amino acid changes in HA and the PB2
RNA polymerase subunit probably facilitate binding to human-type receptors and efficient
replication in mammals, respectively, highlighting the pandemic potential of the novel …
Novel influenza viruses of the H7N9 subtype have infected 33 and killed nine people in China as of 10 April 2013. Their haemagglutinin (HA) and neuraminidase genes probably originated from Eurasian avian influenza viruses; the remaining genes are closely related to avian H9N2 influenza viruses. Several characteristic amino acid changes in HA and the PB2 RNA polymerase subunit probably facilitate binding to human-type receptors and efficient replication in mammals, respectively, highlighting the pandemic potential of the novel viruses.
eurosurveillance.org