Elevated concentration of microvesicles isolated from peripheral blood in breast cancer patients
O Galindo-Hernandez, S Villegas-Comonfort… - Archives of medical …, 2013 - Elsevier
BACKGROUND AND AIMS: Breast cancer is the most common cancer and the main cause
of cancer deaths in women worldwide. Microvesicles (MVs) are fragments of the plasma
membrane secreted from cytoplasmic membrane compartments by normal and malignant
cells. An increase in MV number has been found in peripheral blood of patients with several
diseases including cancer. We hypothesized that MV number and the relative amount of
focal adhesion kinase (FAK) and epidermal growth factor receptor (EGFR) proteins in …
of cancer deaths in women worldwide. Microvesicles (MVs) are fragments of the plasma
membrane secreted from cytoplasmic membrane compartments by normal and malignant
cells. An increase in MV number has been found in peripheral blood of patients with several
diseases including cancer. We hypothesized that MV number and the relative amount of
focal adhesion kinase (FAK) and epidermal growth factor receptor (EGFR) proteins in …