Tumor-derived exosomes: a new source of tumor rejection antigens
Vaccine, 2002•Elsevier
Exosomes are small vesicles released by a broad array of hematopoietic cells. Previous
studies showed that exosomes released by antigen loaded dendritic cells induce immune-
mediated anti-tumor response in mice. Here, we will describe the biochemical properties of
tumor-derived exosomes and, their pre-clinical activity as cancer vaccines.
studies showed that exosomes released by antigen loaded dendritic cells induce immune-
mediated anti-tumor response in mice. Here, we will describe the biochemical properties of
tumor-derived exosomes and, their pre-clinical activity as cancer vaccines.
Exosomes are small vesicles released by a broad array of hematopoietic cells. Previous studies showed that exosomes released by antigen loaded dendritic cells induce immune-mediated anti-tumor response in mice. Here, we will describe the biochemical properties of tumor-derived exosomes and, their pre-clinical activity as cancer vaccines.
Elsevier