A common mitochondrial haplogroup is associated with elevated total serum IgE levels
BA Raby, B Klanderman, A Murphy, S Mazza… - Journal of Allergy and …, 2007 - Elsevier
BACKGROUND: Maternal history of asthma or atopy is among the most consistently
reported risk factors for asthma and atopy in children, yet the molecular basis for this
observation remains unclear. Mitochondria are inherited exclusively through the maternal
line, raising the possibility that sequence variation in the mitochondrial genome contributes
to the pathogenesis of asthma and atopy. OBJECTIVE: We set out to determine whether
common European mitochondrial haplogroups are associated with asthma-related atopic …
reported risk factors for asthma and atopy in children, yet the molecular basis for this
observation remains unclear. Mitochondria are inherited exclusively through the maternal
line, raising the possibility that sequence variation in the mitochondrial genome contributes
to the pathogenesis of asthma and atopy. OBJECTIVE: We set out to determine whether
common European mitochondrial haplogroups are associated with asthma-related atopic …