Differentiation of human pulmonary alveolar epithelial cells revealed by peroxisome changes in pulmonary proteinosis
K Moriguchi, N Higashi, S Kitagawa, K Takase… - … and molecular pathology, 1984 - Elsevier
Regenerating areas of human lungs in pulmonary fibrosis were observed electron
microscopically, and peroxidatic activity of catalase in lung peroxisomes were demonstrated
cytochemically. Proliferation of Type II cells was prominent there, and some of the cells
extended their cytoplasms to cover the denuded basement membrane. Unusual
intermediate cells between Type II and Type I cells were observed. The extension of
cytoplasmic processes with new generation of pinocytotic vesicles strongly suggested a …
microscopically, and peroxidatic activity of catalase in lung peroxisomes were demonstrated
cytochemically. Proliferation of Type II cells was prominent there, and some of the cells
extended their cytoplasms to cover the denuded basement membrane. Unusual
intermediate cells between Type II and Type I cells were observed. The extension of
cytoplasmic processes with new generation of pinocytotic vesicles strongly suggested a …