Chemokines and cytokines in neuroinflammation leading to neuropathic pain
N Kiguchi, Y Kobayashi, S Kishioka - Current opinion in pharmacology, 2012 - Elsevier
There has been recent evidence showing the correlation between neuroinflammation owing
to the chemokine–cytokine network and neuropathic pain. Chemokines and cytokines are
derived from several types of cells in the peripheral and central nervous systems following
nerve injury, and are largely involved in the pathogenesis of neuropathic pain. The roles of
typical inflammatory cytokines such as interleukin-1β have become the recent center of
attention. There is growing evidence that inflammatory chemokines (CCL2, CCL3, and …
to the chemokine–cytokine network and neuropathic pain. Chemokines and cytokines are
derived from several types of cells in the peripheral and central nervous systems following
nerve injury, and are largely involved in the pathogenesis of neuropathic pain. The roles of
typical inflammatory cytokines such as interleukin-1β have become the recent center of
attention. There is growing evidence that inflammatory chemokines (CCL2, CCL3, and …