[HTML][HTML] A highly purified RNA polymerase II elongation control system

DB Renner, Y Yamaguchi, T Wada, H Handa… - Journal of Biological …, 2001 - ASBMB
Studying the sensitivity of transcription to the nucleotide analog 5, 6-dichloro-1-β-d-
ribofuranosylbenzimidazole has led to the discovery of a number of proteins involved in the
regulation of transcription elongation by RNA polymerase II. We have developed a highly
purified elongation control system composed of three purified proteins added back to
isolated RNA polymerase II elongation complexes. Two of the proteins, 5, 6-dichloro-1-β-d-
ribofuranosylbenzimidazole sensitivity-inducing factor (DSIF) and negative elongation factor …