[HTML][HTML] Overview of general physiologic features and functions of vitamin D
HF DeLuca - The American journal of clinical nutrition, 2004 - Elsevier
Vitamin D 3 is a prohormone produced in skin through ultraviolet irradiation of 7-
dehydrocholesterol. It is biologically inert and must be metabolized to 25-hydroxyvitamin D 3
in the liver and then to 1α, 25-dihydroxyvitamin D 3 in the kidney before function. The
hormonal form of vitamin D 3, ie, 1α, 25-dihydroxyvitamin D 3, acts through a nuclear
receptor to carry out its many functions, including calcium absorption, phosphate absorption
in the intestine, calcium mobilization in bone, and calcium reabsorption in the kidney. It also …
dehydrocholesterol. It is biologically inert and must be metabolized to 25-hydroxyvitamin D 3
in the liver and then to 1α, 25-dihydroxyvitamin D 3 in the kidney before function. The
hormonal form of vitamin D 3, ie, 1α, 25-dihydroxyvitamin D 3, acts through a nuclear
receptor to carry out its many functions, including calcium absorption, phosphate absorption
in the intestine, calcium mobilization in bone, and calcium reabsorption in the kidney. It also …