Genetics, diagnostics and therapeutic advances in NAFLD

ME Rinella, AJ Sanyal - Nature reviews Gastroenterology & hepatology, 2015 - nature.com
Nature reviews Gastroenterology & hepatology, 2015nature.com
In 2014, NAFLD was confirmed as the fastest growing aetiology for hepatocellular cancer in
the USA. However, 2014 also saw progress in our understanding of the heritability and
pathogenesis of NAFLD, and an important clinical trial targeting the farnesoid X receptor
pathway has illustrated advances in developing a pharmacological therapy.
In 2014, NAFLD was confirmed as the fastest growing aetiology for hepatocellular cancer in the USA. However, 2014 also saw progress in our understanding of the heritability and pathogenesis of NAFLD, and an important clinical trial targeting the farnesoid X receptor pathway has illustrated advances in developing a pharmacological therapy.
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