[HTML][HTML] Type VI collagen anchors endothelial basement membranes by interacting with type IV collagen

HJ Kuo, CL Maslen, DR Keene, RW Glanville - Journal of Biological …, 1997 - ASBMB
Type VI collagen filaments are found associated with interstitial collagen fibers, around cells,
and in contact with endothelial basement membranes. To identify type VI collagen binding
proteins, the amino-terminal domains of the α1 (VI) and α2 (VI) chains and a part of the
carboxyl-terminal domain of the α3 (VI) chain were used as bait in a yeast two-hybrid system
to screen a human placenta library. Eight persistently positive clones were identified, two
coding the known matrix proteins fibronectin and basement membrane type IV collagen and …