Immune reactive C3d on the surface of myelin sheaths in neuropathy

AP Hays, SSL Lee, N Latov - Journal of neuroimmunology, 1988 - Elsevier
Immunofluorescence studies of sural nerve demonstrated immune reactive C3d and IgM on
the surface of myelin sheaths in seven patients with neuropathy and an anti-myelin-
associated glycoprotein (MAG) IgM M-protein. Similar deposits of C3d and sometimes IgM
were found in four of six patients with acute or chronic inflammatory demyelinating
polyneuropathy and in three of six patients with vasculitic neuropathy (including one with
acquired immunodeficiency syndrome (AIDS)). C3d was not found in 80 patients with other …