[HTML][HTML] Characterization of the localization and proteolytic activity of the SUMO-specific protease, SENP1
D Bailey, P O'Hare - Journal of Biological Chemistry, 2004 - ASBMB
Modification of proteins by small ubiquitin-like modifier (SUMO) plays an important role in
the function, compartmentalization, and stability of target proteins, contributing to the
regulation of diverse processes. SUMO-1 modification can be regulated not only at the level
of conjugation; it may also be reversed by a class of proteases known as the SUMO-specific
proteases. However, current understanding of the regulation, specificity, and function of
these proteases remains limited. In this study, we characterize aspects of the …
the function, compartmentalization, and stability of target proteins, contributing to the
regulation of diverse processes. SUMO-1 modification can be regulated not only at the level
of conjugation; it may also be reversed by a class of proteases known as the SUMO-specific
proteases. However, current understanding of the regulation, specificity, and function of
these proteases remains limited. In this study, we characterize aspects of the …