[HTML][HTML] Genome‐wide association study validation identifies novel loci for atherosclerotic cardiovascular disease

X Chen, S Li, Y Yang, X Yang, Y Liu, W Hu, L Jin… - Journal of thrombosis …, 2012 - Elsevier
Background: Genetic variants influencing lipid levels and risk of coronary artery disease
(CAD) have been identified by recent genome‐wide association studies (GWAS).
Objectives: To test the association of single nucleotide polymorphisms (SNPs) implicated in
lipoprotein metabolism and CAD in GWAS with atherosclerotic cardiovascular disease
(ASCVD, including ischemic stroke [IS] and myocardial infarction [MI] phenotypes). Patients
and methods: A two‐stage genetic association study was conducted in the Chinese Hans …