Blue rubber bleb nevus syndrome: successful treatment with sirolimus
H Yuksekkaya, O Ozbek, M Keser, H Toy - Pediatrics, 2012 - publications.aap.org
Blue rubber bleb nevus syndrome (BRBNS) is a rare disorder with characteristic vascular
malformations of the skin, gastrointestinal system, and, less often, other organ systems. The
characteristic cutaneous lesions consist of deep-blue, soft, rubbery blebs, which are easily
compressible. The most serious complication is abundant gastrointestinal bleeding. We
describe the case of an 8-year-old girl with diagnosed BRBNS who had multiple venous
malformations all over her body, importantly, throughout the gastrointestinal tract, mouth …
malformations of the skin, gastrointestinal system, and, less often, other organ systems. The
characteristic cutaneous lesions consist of deep-blue, soft, rubbery blebs, which are easily
compressible. The most serious complication is abundant gastrointestinal bleeding. We
describe the case of an 8-year-old girl with diagnosed BRBNS who had multiple venous
malformations all over her body, importantly, throughout the gastrointestinal tract, mouth …