B7 family molecules: novel immunomodulators at the maternal-fetal interface
MG Petroff, L Chen, TA Phillips, JS Hunt - Placenta, 2002 - Elsevier
The placenta utilizes both active and passive mechanisms to evade rejection by the
maternal immune system. Recently, the mRNA for two newly cloned members of the B7
family of immunomodulatory cell-associated proteins have been identified in the human term
placenta. In this article, we review the current knowledge of the B7 family member B7-H1,
and discuss how it may participate in modulation of the maternal immune system at the
maternal-fetal interface. B7-H1 has been found to possess immunostimulatory or …
maternal immune system. Recently, the mRNA for two newly cloned members of the B7
family of immunomodulatory cell-associated proteins have been identified in the human term
placenta. In this article, we review the current knowledge of the B7 family member B7-H1,
and discuss how it may participate in modulation of the maternal immune system at the
maternal-fetal interface. B7-H1 has been found to possess immunostimulatory or …