[HTML][HTML] Randomized selection design trial evaluating CD8+-enriched versus unselected tumor-infiltrating lymphocytes for adoptive cell therapy for patients with …

ME Dudley, CA Gross, RPT Somerville… - Journal of Clinical …, 2013 - ncbi.nlm.nih.gov
ME Dudley, CA Gross, RPT Somerville, Y Hong, NP Schaub, SF Rosati, DE White, D Nathan…
Journal of Clinical Oncology, 2013ncbi.nlm.nih.gov
Randomized Selection Design Trial Evaluating CD8+-Enriched Versus Unselected Tumor-Infiltrating
Lymphocytes for Adoptive Cell Therapy for Patients With Melanoma - PMC Back to Top Skip to
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Abstract
Purpose
Adoptive cell therapy (ACT) with autologous tumor-infiltrating lymphocytes (TILs) and high-dose interleukin-2 (IL-2) administered to lymphodepleted patients with melanoma can cause durable tumor regressions. The optimal TIL product for ACT is unknown.
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