Spectrin-and ankyrin-based membrane domains and the evolution of vertebrates
V Bennett, DN Lorenzo - Current topics in membranes, 2013 - Elsevier
Spectrin and ankyrin are membrane skeletal proteins that contribute to mechanical support
of plasma membranes and micron-scale organization of diverse membrane-spanning
proteins. This chapter provides a plausible scenario for the evolution of ankyrin-and spectrin-
based membrane domains with a focus on vertebrates. The analysis integrates recent
phylogenetic information with functional analyses of spectrin and ankyrin in erythrocytes,
axon initial segments and nodes of Ranvier in neurons, T-tubules and intercalated disks of …
of plasma membranes and micron-scale organization of diverse membrane-spanning
proteins. This chapter provides a plausible scenario for the evolution of ankyrin-and spectrin-
based membrane domains with a focus on vertebrates. The analysis integrates recent
phylogenetic information with functional analyses of spectrin and ankyrin in erythrocytes,
axon initial segments and nodes of Ranvier in neurons, T-tubules and intercalated disks of …