Atherosclerosis can be considered as both a chronic inflammatory disease and a lipid
metabolism disorder. Innate immunity pathways have long been suspected to contribute to
the initiation and progression of atherosclerosis. This suggests that crosstalk between lipid
metabolism and innate immunity pathways plays an important role for the development
and/or the prevention of atherosclerosis. However, it is not fully defined how innate immunity
affects lipid metabolism. Macrophages play a central role in atherogenesis through the …