Effect of selenium and vitamin E on risk of prostate cancer and other cancers: the Selenium and Vitamin E Cancer Prevention Trial (SELECT)
SM Lippman, EA Klein, PJ Goodman, MS Lucia… - Jama, 2009 - jamanetwork.com
Context Secondary analyses of 2 randomized controlled trials and supportive epidemiologic
and preclinical data indicated the potential of selenium and vitamin E for preventing prostate
cancer. Objective To determine whether selenium, vitamin E, or both could prevent prostate
cancer and other diseases with little or no toxicity in relatively healthy men. Design, Setting,
and Participants A randomized, placebo-controlled trial (Selenium and Vitamin E Cancer
Prevention Trial [SELECT]) of 35 533 men from 427 participating sites in the United States …
and preclinical data indicated the potential of selenium and vitamin E for preventing prostate
cancer. Objective To determine whether selenium, vitamin E, or both could prevent prostate
cancer and other diseases with little or no toxicity in relatively healthy men. Design, Setting,
and Participants A randomized, placebo-controlled trial (Selenium and Vitamin E Cancer
Prevention Trial [SELECT]) of 35 533 men from 427 participating sites in the United States …