Selenium and its' role in the maintenance of genomic stability

LR Ferguson, N Karunasinghe, S Zhu… - … research/fundamental and …, 2012 - Elsevier
Selenium (Se) is an essential micronutrient for humans, acting as a component of the
unusual amino acids, selenocysteine (Se-Cys) and selenomethionine (Se-Met). Where Se
levels are low, the cell cannot synthesise selenoproteins, although some selenoproteins and
some tissues are prioritised over others. Characterised functions of known selenoproteins,
include selenium transport (selenoprotein P), antioxidant/redox properties (glutathione
peroxidases (GPxs), thioredoxin reductases and selenoprotein P) and anti-inflammatory …