Bone-marrow-derived microglia: myth or reality?

D Soulet, S Rivest - Current opinion in pharmacology, 2008 - Elsevier
Microglia are the immune cells of the central nervous system (CNS). They patrol the brain
environment with their ramifications and they respond quickly in the presence of pathogens
and brain damages. Others and we have recently reported the existence of two different
types of microglia, the resident and the newly differentiated microglia that are derived from
the bone marrow stem cells. Of great interest is the fact that blood-derived microglial cells
are associated with amyloid plaques and these cells are able to prevent the formation or …