Molecular profiling of peripheral blood cells from patients with polycythemia vera and related neoplasms: identification of deregulated genes of significance for …
V Skov, TS Larsen, M Thomassen, CH Riley… - Leukemia research, 2012 - Elsevier
Essential thrombocythemia (ET), polycythemia vera (PV) and primary myelofibrosis (PMF)
are hematopoietic stem cell neoplasms that may be associated with autoimmune or chronic
inflammatory disorders. Earlier gene expression profiling studies have demonstrated
aberrant expression of genes involved in inflammatory responses, mainly being performed
on granulocytes or CD34+ cells. Using gene expression profiling of whole blood from
patients with ET (n= 16), PV (n= 36), and PMF (n= 9), several genes involved in inflammation …
are hematopoietic stem cell neoplasms that may be associated with autoimmune or chronic
inflammatory disorders. Earlier gene expression profiling studies have demonstrated
aberrant expression of genes involved in inflammatory responses, mainly being performed
on granulocytes or CD34+ cells. Using gene expression profiling of whole blood from
patients with ET (n= 16), PV (n= 36), and PMF (n= 9), several genes involved in inflammation …