Development of broadly neutralizing antibodies from autologous neutralizing antibody responses in HIV infection
Collectively, studies over the last year have suggested that the development of HIV-1 Env
immunogens that bind and activate bnAb-like germlines is feasible. However, more
information about the features of Env variants and the host factors that lead to breadth during
natural infection are needed to elicit bnAbs through immunization.
immunogens that bind and activate bnAb-like germlines is feasible. However, more
information about the features of Env variants and the host factors that lead to breadth during
natural infection are needed to elicit bnAbs through immunization.
Summary
Collectively, studies over the last year have suggested that the development of HIV-1 Env immunogens that bind and activate bnAb-like germlines is feasible. However, more information about the features of Env variants and the host factors that lead to breadth during natural infection are needed to elicit bnAbs through immunization.
Lippincott Williams & Wilkins