Biology and treatment of Burkitt's lymphoma

JT Yustein, CV Dang - Current opinion in hematology, 2007 - journals.lww.com
Current opinion in hematology, 2007journals.lww.com
Burkitt's lymphoma is an interesting mature B-cell non-Hodgkin's lymphoma that has
numerous distinct features and clinical variants depending on factors such as geographical
location, immunological status and patient's age. Although the role of the MYC oncogene
has been well studied, we are only now appreciating the defining molecular characteristics
of this disease, and using these advances to improve treatment options for patients.
Summary
Burkitt's lymphoma is an interesting mature B-cell non-Hodgkin's lymphoma that has numerous distinct features and clinical variants depending on factors such as geographical location, immunological status and patient's age. Although the role of the MYC oncogene has been well studied, we are only now appreciating the defining molecular characteristics of this disease, and using these advances to improve treatment options for patients.
Lippincott Williams & Wilkins