Amyotrophic lateral sclerosis in an urban setting: a population based study of inner city London
CA Johnston, BR Stanton, MR Turner, R Gray… - Journal of …, 2006 - Springer
Journal of neurology, 2006•Springer
Sirs: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease primarily affecting
cortical and spinal motor neurons. There have been several previous population studies,
reporting incidences between 0.44 and 3.2 per 100,000 person-years [1, 2].As a preliminary
step in establishing a population register for ALS in South-East England, we have identified
all prevalent cases in the London Boroughs of Lambeth, Southwark and Lewisham (LSL)
between 1 January 1997 and 31 July 2004. Cases were identified from multiple sources to …
cortical and spinal motor neurons. There have been several previous population studies,
reporting incidences between 0.44 and 3.2 per 100,000 person-years [1, 2].As a preliminary
step in establishing a population register for ALS in South-East England, we have identified
all prevalent cases in the London Boroughs of Lambeth, Southwark and Lewisham (LSL)
between 1 January 1997 and 31 July 2004. Cases were identified from multiple sources to …
Sirs: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease primarily affecting cortical and spinal motor neurons. There have been several previous population studies, reporting incidences between 0.44 and 3.2 per 100,000 person-years [1, 2].
As a preliminary step in establishing a population register for ALS in South-East England, we have identified all prevalent cases in the London Boroughs of Lambeth, Southwark and Lewisham (LSL) between 1 January 1997 and 31 July 2004. Cases were identified from multiple sources to ensure ascertainment was as complete as possible, but it is important to recognise that this register covers a relatively small population, with a high rate of migration in and out of the area.
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