β-Blockers in diabetic patients with heart failure
G Santulli - JAMA Internal Medicine, 2015 - jamanetwork.com
To the Editor Pasternak et al1 report that the effectiveness of metoprolol succinate and
carvedilol in patients with heart failure is similar. Counteracting neurohormonal
hyperactivation through β-blockers represents an established cornerstone for the treatment
of heart failure. However, owing to their glycometabolic effects there are some issues
concerning the use of β-blockers in patients with diabetes mellitus, which account for
approximately one-third of patients with heart failure. 2, 3 The large and accurate population …
carvedilol in patients with heart failure is similar. Counteracting neurohormonal
hyperactivation through β-blockers represents an established cornerstone for the treatment
of heart failure. However, owing to their glycometabolic effects there are some issues
concerning the use of β-blockers in patients with diabetes mellitus, which account for
approximately one-third of patients with heart failure. 2, 3 The large and accurate population …