Combined Use of Mycobacterium tuberculosis–Specific CD4 and CD8 T-Cell Responses Is a Powerful Diagnostic Tool of Active Tuberculosis

V Rozot, A Patrizia, S Vigano… - Clinical Infectious …, 2015 - academic.oup.com
V Rozot, A Patrizia, S Vigano, J Mazza-Stalder, E Idrizi, CL Day, M Perreau…
Clinical Infectious Diseases, 2015academic.oup.com
Immune-based assays are promising tools to help to formulate diagnosis of active
tuberculosis. A multiparameter flow cytometry assay assessing T-cell responses specific to
Mycobacterium tuberculosis and the combination of both CD4 and CD8 T-cell responses
accurately discriminated between active tuberculosis and latent infection.
Abstract
Immune-based assays are promising tools to help to formulate diagnosis of active tuberculosis. A multiparameter flow cytometry assay assessing T-cell responses specific to Mycobacterium tuberculosis and the combination of both CD4 and CD8 T-cell responses accurately discriminated between active tuberculosis and latent infection.
Oxford University Press