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URL: http://scholar.google.com/scholar_lookup?title=Pharmacodynamics+of+2-%5B4-%5B%281E%29-1-%28hydroxyimino%29-2%2C3-dihydro-1H-inden-5-yl%5D-3-%28pyridine-4-yl%29-1H-pyrazol-1-yl%5Dethan-1-ol+%28GDC-0879%29%2C+a+potent+and+selective+B-Raf+kinase+inhibitor%3A+understanding+relationships+between+systemic+concentrations%2C+phosphorylated+mitogen-activated+protein+kinase+kinase+1+inhibition%2C+and+efficacy.&year=2009&author=Wong&journal=J+Pharmacol+Exp+Ther.&volume=329&issue=1&pages=360-367&doi=10.1124%2Fjpet.108.148189&pmid=19147858