[HTML][HTML] Identification of a new family of protein phosphatase 2A regulatory subunits (∗)

B McCright, DM Virshup - Journal of Biological Chemistry, 1995 - ASBMB
Protein phosphatase 2A (PP2A) is a major intracellular protein phosphatase that regulates
multiple aspects of cell growth and metabolism. The ability of this widely distributed
heterotrimeric enzyme to act on a diverse array of substrates is largely controlled by the
nature of its regulatory B subunit. Only two gene families encoding endogenous B subunits
have been cloned to date, although the existence of several additional regulatory subunits is
likely. We have identified by two-hybrid interaction a new human gene family encoding …