Long-term potentiation--a decade of progress?
RC Malenka, RA Nicoll - Science, 1999 - science.org
RC Malenka, RA Nicoll
Science, 1999•science.orgLong-term potentiation of synaptic transmission in the hippocampus is the leading
experimental model for the synaptic changes that may underlie learning and memory. This
review presents a current understanding of the molecular mechanisms of this long-lasting
increase in synaptic strength and describes a simple model that unifies much of the data that
previously were viewed as contradictory.
experimental model for the synaptic changes that may underlie learning and memory. This
review presents a current understanding of the molecular mechanisms of this long-lasting
increase in synaptic strength and describes a simple model that unifies much of the data that
previously were viewed as contradictory.
Long-term potentiation of synaptic transmission in the hippocampus is the leading experimental model for the synaptic changes that may underlie learning and memory. This review presents a current understanding of the molecular mechanisms of this long-lasting increase in synaptic strength and describes a simple model that unifies much of the data that previously were viewed as contradictory.
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