Good clinical and radiological response to BRAF inhibitor in patient with metastatic thin melanoma
KI Quintyne, S Baker, F Wallis, R Gupta - Case Reports, 2012 - casereports.bmj.com
The authors herein report the case of a 32-year-old man with advancing metastatic
malignant melanoma, who has progressed through all previous lines of therapy, presenting
with ongoing respiratory tract symptoms of exertional shortness of breath and cough. CT
restaging confirmed clinical findings of deteriorating pulmonary disease; histological review
revealed V600E BRAF mutation. He was started on targeted biological therapy with BRAF
inhibitor GSK2118436, and is having a good clinical and radiological response without …
malignant melanoma, who has progressed through all previous lines of therapy, presenting
with ongoing respiratory tract symptoms of exertional shortness of breath and cough. CT
restaging confirmed clinical findings of deteriorating pulmonary disease; histological review
revealed V600E BRAF mutation. He was started on targeted biological therapy with BRAF
inhibitor GSK2118436, and is having a good clinical and radiological response without …
[HTML][HTML] Novel treatment (new drug/intervention; established drug/procedure in new situation): Good clinical and radiological response to BRAF inhibitor in patient with …
KI Quintyne, S Baker, F Wallis, R Gupta - BMJ Case Reports, 2012 - ncbi.nlm.nih.gov
The authors herein report the case of a 32-year-old man with advancing metastatic
malignant melanoma, who has progressed through all previous lines of therapy, presenting
with ongoing respiratory tract symptoms of exertional shortness of breath and cough. CT
restaging confirmed clinical findings of deteriorating pulmonary disease; histological review
revealed V600E BRAF mutation. He was started on targeted biological therapy with BRAF
inhibitor GSK2118436, and is having a good clinical and radiological response without …
malignant melanoma, who has progressed through all previous lines of therapy, presenting
with ongoing respiratory tract symptoms of exertional shortness of breath and cough. CT
restaging confirmed clinical findings of deteriorating pulmonary disease; histological review
revealed V600E BRAF mutation. He was started on targeted biological therapy with BRAF
inhibitor GSK2118436, and is having a good clinical and radiological response without …