ABC of clinical haematology: macrocytic anaemias

V Hoffbrand, D Provan - Bmj, 1997 - bmj.com
V Hoffbrand, D Provan
Bmj, 1997bmj.com
Macrocytosis is a rise in the mean cell volume of the red cells above the normal range (in
adults 80-95 fl (femtolitres). It is detected with a blood count, in which the mean cell volume,
as well as other red cell indices, is measured. The mean cell volume is lower in children
than in adults, with a normal mean of 70 fl at age 1 year, rising by about 1 fl each year until
adult volumes are reached at puberty.
Macrocytosis is a rise in the mean cell volume of the red cells above the normal range (in adults 80-95 fl (femtolitres). It is detected with a blood count, in which the mean cell volume, as well as other red cell indices, is measured. The mean cell volume is lower in children than in adults, with a normal mean of 70 fl at age 1 year, rising by about 1 fl each year until adult volumes are reached at puberty.
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