Distribution and properties of glucagon immunoreactivity in the digestive tract of various mammals: an immunohistochemical and immunochemical study

LI Larsson, J Holst, R Håkanson, F Sundler - Histochemistry, 1975 - Springer
LI Larsson, J Holst, R Håkanson, F Sundler
Histochemistry, 1975Springer
Numerous epithelial cells in the oxyntic gland area of the stomach of cat and dog appear to
store pancreatic-type glucagon, as evidenced by immunohistochemistry and—in the case of
the dog—also by radioimmunoanalysis. No glucagon immunoreactive cells are found in the
antropyloric mucosa. Disseminated cells in the intestinal mucosa store gut-type glucagon. In
all species studied, these cells predominate in ileum and colon.
Summary
Numerous epithelial cells in the oxyntic gland area of the stomach of cat and dog appear to store pancreatic-type glucagon, as evidenced by immunohistochemistry and—in the case of the dog—also by radioimmunoanalysis. No glucagon immunoreactive cells are found in the antropyloric mucosa. Disseminated cells in the intestinal mucosa store gut-type glucagon. In all species studied, these cells predominate in ileum and colon.
Springer